Table 3 Pearson correlation coefficient between the parameters describing the full DFE and Ne for all amino acid changing mutations and GC-conservative mutations
ModelDFE parametersAllGC-conservative
M3S|Sd|0.91 (0.88 to 0.93)0.75 (0.88 to 0.56)
|sd|0.76 (0.66 to 0.85)0.44 (0.04 to 0.77)
% Sd ≤ -100.88 (0.82 to 0.93)0.67 (0.50 to 0.83)
% -10 < Sd ≤ -1−0.88 (−0.93 to −0.82)−0.68 (−0.83 to −0.50)
% -1 < Sd ≤ 0−0.88 (−0.93 to −0.82)−0.67 (−0.83 to −0.50)
Model average (M3I, M3S, M2I, M2S)pb−0.18 (−0.48 to 0.20)−0.32 (−0.68 to 0.10)
Sb−0.07 (−0.48 to 0.28)−0.35 (−0.52 to 0.06)
pb × Sb−0.14 (−0.48 to 0.16)−0.32 (−0.51 to 0.12)
  • The 95% confidence intervals in parentheses are based on 100 bootstrap replicates. All these correlations have been cross-validated using a phylogenetically aware regression analysis.