Table 1 Parameters included in each model used for estimating the DFE
ModelSdbSbpbriεancθ
0FittedFittedFittedFitted10Fitted
1FittedFittedFittedFittedFitted0Fitted
2FittedFittedFittedFittedFittedFittedFitted
3FittedFitted00Fitted0Fitted
4FittedFitted00FittedFittedFitted
  • In gray are the two models on which most of our results are based. Sd is the mean population scaled selection coefficient of new additive deleterious mutations (s ≤ 0), b is the shape parameter of the deleterious DFE, Sb is the mean population scaled selection coefficient of new additive beneficial mutations, pb is the proportion of new beneficial mutations (s > 0), ri is the series of nuisance parameters used to control for potential distorters of the uSFS, εanc is the polarization error, and θ is the population scaled mutation rate (4Neμ).