Table 2 Additional caspofungin MICs at 30°
Gene locus tagGene product mutatedMIC (µg/ml)
WTNA25
CNAG_04796Calcineurin A subunit3.125
CNAG_01744Crz1 transcription factor12.5
CNAG_05581Chitin synthase 33.125
CNAG_00293Ras1 GTPase25
CNAG_05348Cdc42 GTPase25
CNAG_05968Cdc420 GTPase25
CNAG_04243Cdc24 guanine nucleotide exchange factor25
CNAG_06165Ste20 PAK kinase25
CNAG_04761Ras2 GTPase25
CNAG_05998Rac2 GTPase25
CNAG_02883Rac1 GTPase25
CNAG_05925Septin Cdc325
CNAG_01740Septin Cdc1225
CNAG_05970PAK kinase Pak125
  • MIC, minimal inhibitory concentration; WT, wild-type. PAK: p21-activated protein kinase.