Table 5 Computation time in minutes to estimate permutation P-values for the condition × gene interactions for each plate (a total of ∼1 million interactions)
Plate123456Total
MLM2.822.783.463.282.823.0018.16
S scores77.6272.5993.3794.2276.3177.32491.42
• The computational advantages of matrix linear models are even more apparent when permutation P-values are desired. MLM, matrix linear model.