Table 2 False-positive rate for MLMs, calculated as the proportion of P-values below cutoffs of 0.01, 0.05, and 0.1, based on 100 simulated data sets
Plate123456
0.010.010 (0.009, 0.011)0.010 (0.009, 0.011)0.010 (0.009, 0.010)0.010 (0.010, 0.010)0.010 (0.009, 0.011)0.010 (0.009, 0.011)
0.050.050 (0.049, 0.051)0.050 (0.049, 0.051)0.050 (0.049, 0.051)0.050 (0.049, 0.051)0.050 (0.049, 0.051)0.050 (0.049, 0.051)
0.10.100 (0.098, 0.102)0.100 (0.098, 0.102)0.100 (0.099, 0.101)0.100 (0.099, 0.101)0.100 (0.098, 0.102)0.100 (0.098, 0.101)
  • Our method appears to preserve type I error.