| Genotype | Adult overproliferation (%) | na | Overproliferation severity in adultsb |
|---|---|---|---|
| gld-1 | 100 | >100 | ++ |
| gld-1; glp-1 | 0 | 20 | – |
| fog-1 gld-1;glp-1 | 100 | 20 | + |
| gld-1 prom-1 | 100 | >100 | +++ |
| gld-1 prom-1; glp-1 | 100 | >100 | + |
| gld-2 prom-1 | 100 | >100 | ++ |
| gld-2 prom-1; glp-1 | 100 | >100 | ++ |
| prom-1; gld-3 | 100 | 90 | ++ |
| prom-1; gld-3; glp-1 | 100 | 45 | + |
| gld-1 skr-2 | 100 | 100 | ++ |
| gld-1 skr-2; glp-1 | 100 | 30 | + |
| gld-2 skr-2 | 28 | 112 | + |
| gld-2 skr-2; glp-1 | Glpc | 30 | – |
| skr-2; gld-3 | 91 | 121 | + |
| skr-2; gld-3; glp-1 | 100 | 196 | + |
| gld-4d | 0 | 30 | – |
| gld-4 prom-1e | 100 | 30 | + |
↵a Number of gonad arms analyzed.
↵b Overproliferation severity was qualitatively determined based on number of S-phase nuclei. Overproliferation of gld-1 mutant germline is arbitrarily taken as ++, and gonads from age-matched animals of different genotypes are classified as less severe (+) or more severe (+++) than gld-1 mutant germlines.
↵c All germ cells entered meiosis but are arrested with a pachytene-like morphology.
↵d Hermaphrodites grown at 25°.
↵e Hermaphrodites grown at 25°.