Table 2 List of all pals genes
Linkage GroupGeneCosmid-Based NameWB Gene IDLocationProtein Size (kDa)aSimilarity to PALS-22bUpregulated After Microspiridal and/or Viral InfectioncExpression Enrichment (ModEncode)d
LGIpals-1F15D3.8WBGene00008858I:9.2634.9YesBroad
pals-2C17H1.3WBGene00007656I:17.2245.2YeseMale L4
pals-3C17H1.4WBGene00007657I:17.2239.2YeseMale L4
pals-4C17H1.5WBGene00007658I:17.2240.5YesMale L4
pals-5C17H1.6WBGene00007659I:17.2235.4YesMale L4
pals-6C17H1.7WBGene00007660I:17.2246.8YesMale L4
pals-7C17H1.8WBGene00007661I:17.2239.3YeseMale L4
pals-8C17H1.9WBGene00007662I:17.2241.1YeseMale L4
pals-9C17H1.10WBGene00044237I:17.2234.9YesMale L4
pals-10C17H1.11WBGene00044711I:17.228.4Male L4
pals-11C17H1.13WBGene00044708I:17.2238.5YesMale L4
pals-12C17H1.14WBGene00044709I:17.2246.4YesMale L4
pals-13Y26D4A.8WBGene00012505I:17.2243.5Male L4
pals-14F22G12.1WBGene00009061I:17.2241.3YesMale L4
pals-15F22G12.7WBGene00044707I:17.2241.7YesMale L4
LGIIIpals-16Y82E9BR.4WBGene00022337III:−21.9037.7Broad
pals-17Y82E9BR.13WBGene00022346III:−21.90303e−05YesBroad
pals-18Y82E9BR.21WBGene00022353III:−21.9029.2Broad
pals-19Y82E9BR.23WBGene00044761III:−21.9030.63e−05Broad
pals-20Y82E9BR.25WBGene00194746III:−21.9027.5Low
pals-21Y82E9BR.32WBGene00255597III:−21.9020.73e−12Low
pals-40Y82E9BR.11WBGene00022344III:−21.90244e−06YesLow
pals-22C29F9.1WBGene00016216III:−26.9832.70.0Broad
pals-23C29F9.3WBGene00016218III:−26.9834.76e−05Broad
pals-24C29F9.4WBGene00016219III:−26.9835.72e−10Broad
pals-25T17A3.2WBGene00020540III:−26.9834.72e−06Broad
pals-26B0284.1WBGene00007131III:−3.1849.2YesBroad
pals-27B0284.2WBGene00007132III:−3.1848.2YeseBroad
pals-28B0284.4WBGene00007134III:−3.1848YeseMale L4
LGIVpals-29T27E7.6WBGene00012091IV:12.2048.47e−05YesMale L4 + dauer
pals-30Y57G11B.1WBGene00013294IV:12.2348.93e−04YesBroad
LGVpals-31F48G7.2WBGene00018614V:−19.9725.6YesBroad
pals-32C31B8.4WBGene00016281V:−12.8643.79e−05YeseMale L4 + dauer
pals-33W08A12.4WBGene00021081V:−8.2452YeseMale L4 + dauer
pals-34F26D11.6WBGene00017823V:0.9819.1broad
pals-36fC54D10.12WBGene00044787V:4.2255.42e−04YesMale L4 + dauer
pals-37C54D10.14WBGene00138721V:4.2287.3YeseMale L4 + dauer
pals-38C54D10.8WBGene00008302V:4.2248.1YeseMale L4 + dauer
pals-39C54D10.7WBGene00008301V:4.2248.52e−05YesMale L4 + dauer
  • Protein family assignments made by either Interpro (IPR026673) or Panther (PTHR21707), v9.0. A newer release of Panther does not include pals-7, 10, or 11 in the ALS2CR12 family, yet the sequence similarity of these genes to neighboring pals genes is clear. WB Gene ID, WormBase gene identifier.

  • a Protein size of largest predicted isoform.

  • b PSI Blast e-value. Similarities only above e−04 threshold are shown.

  • c Twenty-eight pals genes upregulated in response to microsporidial and/or viral infection according to Bakowski et al. (2014) and Chen et al. (2017) (out of 218 significantly upregulated genes).

  • d According to Celniker et al. (2009).

  • e Ten pals genes upregulated after cadmium exposure according to Cui et al. (2007) (out of 237 significantly upregulated genes).

  • f Possibly a pseudogene.