Notation | Definition |
---|---|

K | No. of mutants |

D | Total no. of reads per sampling time point (sequencing depth) |

Initial population size of mutant i | |

(Exponential) growth rate of mutant i | |

No. of mutants of type i at time t | |

Vector of the observed no. of sequencing reads sampled at time t | |

Relative frequency of mutant i at time t | |

τ | No. of samples taken |

Duration of the experiment | |

T | No. of sampling time points |

Selection coefficient of mutant i |