Table 3 Deletions in the trio samples that are associated with disease susceptibility and drug response
ChromosomeStartStopNA12878NA12891NA12892Gene(s)Gene descriptionDisease susceptibility
1109687501109714725del/+del/deldel/+GSTM1Glutathione S-transferase Mu‐1Reduced ability to metabolize certain chemical carcinogens and toxins, increasing susceptibility to various cancers and to aplastic anemia
1152570855152621659del/+del/del+/+LCE3B, LCE3CLate cornified envelope 3B, CIncreased susceptibility to psoriasis
1207535283207565105del/+del/deldel/+CR1Complement component receptor 1Malarial resistance; determinant of Knops system blood group
195162893751649902del/+del/del+/+SIGLEC14Sialic acid binding Ig-like lectin 14Increased susceptibility to group B Streptococcus