Table 1 Values of heritability, sample size, prevalence, group size, and sampling frequency (when infection time was assumed unknown) considered in the simulated epidemics for validation of the dnIGE model
Susceptibility and infectivity h2a,bInfectivity h2cSample sizeaPrevalencedGroup sizebSampling frequency for unknown infection timese
0.2
0.45000.32
0.10.42
0.330.55
0.40.61010
0.670.730
0.80.820000.860
0.920
1
  • The base scenario assumed the values in boldface type and known infection times. Unknown environmental variance was set at 1.

  • a To evaluate the effect of heritability and sample size on estimates of heritability and effective contact rates (Figure 2 and Figure S1).

  • b To evaluate the effect of heritability and group size on heritability estimates, prediction accuracies, and sire ranking (Figure 4 and Figure S2).

  • c To evaluate the effect of genetic variation of infectivity on prediction accuracies (Figure 3).

  • d To evaluate the effect of disease prevalence on prediction accuracies (Figure 5).

  • e To evaluate the effect of sampling frequency on prediction accuracies (Figure 6).