Table 1 Summary of rates of tract length change calculated from liquid, colony, and microcolony time courses
GenotypeRates of tract length changes
Liquida (95% C.I.)bColony (95% C.I.)Microcolony (95% C.I)
MSH3(CTG)1.2 × 10−3 (9.0 × 10−4 to 1.6 × 10−3)1.5 × 10−2 (1.2 × 10−2 to 1.9 × 10−2)3.5 × 10−2 (2.8 × 10−2 to 4.2 × 10−2)e
MSH3(CAG)3.1 × 10−3 (2.4 × 10−3 to 3.4 × 10−3)NDcND
msh3Δ(CTG)3.1 × 10−4 (1.3 × 10−4 to 6.0 × 10−4)3.6 × 10−3 (1.5 × 10−3 to 7.2 × 10−3)d1.6 × 10−2 (1.1 × 10−2 to 2.2 × 10−2)f
msh3Δ(CAG)1.3 × 10−4 (2.9 × 10−4 to 3.7 × 10−4)NDND
MSH3(CTG)25<5 × 10−5g,hND<1.2 × 10−3g,h
MSH3(CAG)255.1 × 10−5hNDND
  • a Expansions only.

  • b 95% C.I.s determined by F-statistic.

  • c Not determined.

  • d Predominantly contractions.

  • e Slight bias toward expansions.

  • f Bias toward contractions.

  • g No tract changes observed.

  • h Low numbers precluded accurate calculation of 95% C.I.