True | n | Method | Mean (SD) | 2.5% | 97.5% | Mean C.I. width | Coverage |
---|---|---|---|---|---|---|---|

Two samples (sample at t = 0, 8) | |||||||

1000 | 100 | 1,059.7 (253.5) | 699.8 | 1,657.8 | — | — | |

MLNE | 1,080.7 (260.7) | 711.3 | 1,695.4 | 1,283.3 | 960 | ||

1,033.2 (247.3) | 684.1 | 1,604.8 | 1,195.5 | 956 | |||

5000 | 500 | 5,272.4 (1,164.5) | 3,534.1 | 8,056.8 | — | — | |

MLNE | 5,276.7 (1,166.7) | 3,539.9 | 8,083.9 | 6,046.3 | 970 | ||

5,217.1 (1,149.6) | 3,501.6 | 7,958.1 | 5,957.4 | 967 | |||

Three samples (sample at t = 0, 4, 8) | |||||||

1000 | 100 | 1,107.8 (638.8) | 661.8 | 2,050.7 | — | — | |

MLNE | 1,076.6 (243.9) | 734.9 | 1,704.6 | 1,134.2 | 957 | ||

1,030.9 (226.8) | 709.4 | 1,605.4 | 1,054.0 | 960 | |||

5000 | 500 | 5,567.7 (2,038.2) | 3,165.9 | 10708.0 | — | — | |

MLNE | 5,254.0 (1,153.4) | 3,530.2 | 8,198.1 | 5,427.4 | 950 | ||

5,202.0 (1,138.5) | 3,495.9 | 8,008.4 | 5,352.2 | 953 |

For each parameter setting, 1000 replicate populations were simulated and all three methods are used to estimate . The true , sample size per generation, and number of temporal samples are shown. A total of 500 unlinked loci are used in each run and the initial allele frequencies are sampled from the uniform distribution. The mean, standard deviation, 2.5 and 97.5 percentiles of the 1000 runs are reported. For MLNE and , the mean width of the 95% confidence interval (C.I.) is also computed. The last column shows the number of C.I.’s (of 1000 simulations) that cover the true value .