Table 2 Mutations observed in WT and ∆8 MA lines following the long-term MA experiment
WT∆8
Substitutions12312A2B3456
Position
 Noncoding100471086410
 Nonsense0001100001
 Missense1022261481010
 Silent0212446804
Indels
Position
 Noncoding1103397421
 Coding2010111102
All mutations53412183036271628
Mutation rate (×10−10)2.81.72.212.71931.837.129.616.929.6
Mean (×10−10)2.225.3
  • Mutation distributions for each MA line are shown. Mutation rates were calculated based on the total number of substitutions and small indels per site per generation. The entire list of mutations together with positions and nucleotide changes is shown in Figure S5 and Figure S6.