Table 2 Hub genes connected to nine or more other genes in the eQTL network
GeneChrPathwayLocationDistanceh2η2Deg.
STE2VIMating reg.IIINA0.890.8323
YKL177WXIMating reg.IIINA0.770.7821
STE3XIMating reg.IIINA0.900.8421
BAR1IXMating reg.IIINA0.830.8220
MF(ALPHA)1XVIMating reg.IIINA0.840.8220
STE6XIMating reg.IIINA0.950.9019
AFB1XIIMating reg.IIINA0.930.8619
HMLALPHA2IIIMating reg.III1881560.550.7018
MATALPHA1IIIMating reg.III7320.980.8518
HMLALPHA1IIIMating reg.III1878920.840.8217
YCL065WIIIMating reg. (*)III1874230.940.7815
YCR041WIIIMating reg. (*)III2630.680.7015
MATALPHA2IIIMating reg.III9960.630.7314
ASP3-3XIINitr. starvationXII145380.980.8814
ASP3-1XIINitr. starvationXII108061.000.8913
ASP3-2XIINitr. starvationXII50460.940.8413
LEU1VIILeu biosynthesisIIINA0.930.7612
YCR097W-AIIIMating reg. (*)III1059440.750.8311
HMRA1IIIMating reg.III882780.630.8010
BAT1VIIILeu biosynthesisIIINA0.830.6810
OAC1XILeu biosynthesisIIINA0.900.6810
ASP3-4XIINitr. starvationXII181900.980.8510
SCW11VIIDaugh. cell sep.IINA0.860.809
MFA2XIVMating reg.IIINA0.840.789
  • The column “Pathway” specifies the primary pathway or molecular process in which the gene is involved, where (*) indicates that the gene has unknown function and its pathway has been predicted using the eQTL network. The column “Location” reports the chromosomes where the gene’s eQTLs are located. When both gene and eQTLs are in the same chromosome, the column distance reports the average distance between them. Columns h2 and η2 report, respectively, the narrow-sense heritability and the fraction of variance explained by the eQTL. The column “Deg.” (degree) gives the number of associated genes in the network.