Table 3 Summary of C. parasitica vic-associated genes identified at the molecular level
GeneaP/IbAllelic/nonallelicProtein featuresGene disruption increases virus transmissionc
vic1aPAllelicdHET domainYes
vic1b-2INonelleiceDUF domainYes
vic1c-1INDfLTR retrotransposonND
vic1d-1INDHET domainND
vic2PNonallelicePatatin-like phospholipaseYes
vic3aPNonalleliceHypothetical proteinYes
vic3bPNonalleliceLife guard-1-likeYes
vic4-1INDProtein kinase c-likeNAg
vic4-2INDNACHT + WD40 domainsNA
vic6PNonallelicHET domainYes
pix6PNonallelicDUF1040 domainYes
vic7PNonalleliceHET domainYes
  • a Molecular identification of vic2, vic4, vic6, and vic7 reported in Choi et al. (2012). Molecular identification of vic1 and vic3 reported in this study. Allele specificity is indicated for idiomorphic genes and not polymorphic genes.

  • b P, polymorphic; I, idiomorphic.

  • c Transmission increased when the disrupted strain was paired with a nonmutant strain that is heteroallelic only at the vic locus being analyzed, e.g., Δvic1a-2 (2211-22) vs. EU31 (1211-22).

  • d Potential allelic interaction that requires vic1a-1 disruption for confirmation.

  • e Inferred as nonallelic based on the presence of two polymorphic or idiomorphic genes at locus and on the observation that incompatibility reaction is not eliminated when one gene at locus is disrupted.

  • f ND, not determined.

  • g NA, not applicable. Virus transmission is not restricted by allelic differences at vic4.