Table 1 Percentage of crossovers attributed to each pathway in the early two-pathway paradigm
ClassType of crossoverDefining proteinsPercentage of crossovers
ScSpCeAtDm
IInterferingMsh4–Msh550–70010075–850a
IINoninterferingMus81–Mms42010009–12<10
  • Sc, Saccharomyces cerevisiae; Sp, Schizosaccharomyces pombe; Ce, Caenorhabditis elegans; At, Arabidopsis thaliana; Dm, Drosophila melanogaster. See text for references.

  • a A recent study shows that at least 90% of crossovers in Drosophila melanogaster require the mei-MCM complex, which appears to perform a function similar to that of Msh4–Msh5 (Kohl et al. 2012).