Table 2 Analysis of survival of Top2m/Top2Df9043 larvae at 25°
Allele nameaAllele classification% pupationb
Top2+Wild-type98b (100)c
Df 17Deletion49 (106)
Df 35Deletion66 (103)
17-1Missense73 (100)
17-2Missense72 (100)
17-3Missense92 (120)
17-5Missense,51 (142)
Nonsense
17-6Missense80 (120)
17-7Nonsense49 (135)
35-1Missense82 (100)
35-2Nonsense66 (110)
35-3Missense26 (141)
35-5Missense88 (100)
35-6Missense83 (100)
35-12Missense80 (100)
35-13Missense82 (136)
35-14Nonsense38 (104)
  • Boldface type indicates hypomorphic alleles, strains that showed significant viability (P < 0.04) relative to both Top2Df17 and Top2Df35.

  • a Maternally transmitted mutant Top2m, paternally transmitted mutant Top2Df9043.

  • b Percentage of pupation was determined by dividing the total number of observed pupae by the total number of larvae placed in each vial, multiplied by 100.

  • c Total number scored.