Table 2 Significantly enriched GO terms in the top empirical 0.1% of windows in each population, continued
PopulationStatisticGO termName of GO termP-valueWindowsGenes
MandenkaXP-EHH CEUGO:0007588Excretion0.001252HMOX1, KCNK5
XP-EHH CEUGO:0006813Potassium ion transport0.008553ABCC8, KCNJ11, KCNJ12, KCNK5
XP-EHH CEUGO:0045893Positive regulation of transcription, DNA-dependent0.008052MAP2K3, TCF3
XP-EHH CEUGO:0016311Dephosphorylation0.013352PTPRS, PTPRN2
XP-EHH YRIGO:0002504 (also P)Antigen processing and presentation of peptide or polysaccharide antigen via MHC Class II0.02HLA-DRB5, HLA-DRB9, HLA-DQB1, HLA-DQA1
XP-EHH YRIGO:0019882 (also P)Antigen processing and presentation0.000752HLA-DRB5, HLA-DRA, HLA-DRB9, HLA-DQB1, HLA-DQA1
XP-EHH YRIGO:0006955 (P)Immune response0.005753IL5, HLA-DRB5, HLA-DRA, HLA-DRB9, HLA-DQB1, HLA-DQA1
XP-EHH KHBGO:0050850Positive regulation of calcium-mediated signaling0.02FCER1, P2RX5
XP-EHH KHBGO:0009991Response to extracellular stimulus0.02RASGRP4, RPS19
YorubaXP-EHH MKKGO:0051056Regulation of small GTPase mediated signal transduction0.00532NF1, RAPGEF4
XP-EHH MKKGO:0042552Myelination0.00852SBF2, GAL3ST1
XP-EHH MKKGO:0050890Cognition5x10−52CTNS, NF1
XP-EHH MKKGO:0007420Brain development0.008252CTNS, NF1
XP-EHH MKKGO:0007507Heart development0.013352PKP2, NF1
XP-EHH KHBGO:0050850Positive regulation of calcium-mediated signaling0.00022FCER1A, P2RX5
XP-EHH KHBGO:0009653Anatomical structure morphogenesis0.0062GCM1, ROD1
XP-EHH KHBGO:0007243Intracellular protein kinase cascade0.00912GSG2, ICK
HapMap YRIXP-EHH CEUGO:0007588Excretion0.00132SCNN1B, HMOX1
XP-EHH CEUGO:0001666Response to hypoxia0.003952SCNN1B, HMOX1
XP-EHH CEUGO:0006814Sodium ion transport0.020652SCNN1B, ACCN5
XP-EHH CEUGO:0006355Regulation of transcription, DNA-dependent0.008357CAMTA1, SCMH1, TCF3, JMJD2B, MCM5, AC093376.5, DLX5, DLX6
XP-EHH MKKGO:0048593Camera-type eye morphogenesis0.000152NF1, RING1
XP-EHH MKKGO:0030199Collagen fibril organization0.00032NF1, COL11A2
XP-EHH MKKGO:0030183B cell differentiation0.000952CD79A, POU1F1
XP-EHH MKKGO:0006836Neurotransmitter transport0.001852SLC32A1, SLC6A20
XP-EHH MKKGO:0006512Ubiquitin cycle0.00214USP31, RING1, TULP4, HECW1
XP-EHH MKKGO:0006869 (also P)Lipid transport0.003852OSBP2, APOL5
XP-EHH MKKGO:0006955 (also P)Immune response0.005253CD79A, CCR9, AL645940.4, AL645931.7, HLA-DPB1, HLA-DPA1
XP-EHH KHBGO:0050850Positive regulation of calcium-mediated signaling0.00012FCER1A, P2RX5
XP-EHH KHBGO:0051056Regulation of small GTPase-mediated signal transduction0.005052SIPA1L3, RASGRP4
  • Refer to the Table 1 legend. Next to a GO term, (also P) indicates that the term is significant both when examining PANTHER and when examining all GO terms.