Table 1  Comparison of RNA editing percentage with human homologs
Transcript and editing site in rat RefSeqMean editing level in Na 1-hr treatment (%, n = 4 cultures)Standard error of the mean (%)Previously reported human editing levels at homologous site (%)
Blcap K15R16.51.111–18, various brain regions (Li et al. 2009)
Blcap Q5R28.01.08–16, various brain regions (Li et al. 2009)
Blcap Y2C42.90.6∼30, cerebellum (Kwak et al. 2008)
Cadps E1186G37.81.220–26, various brain regions (Li et al. 2009)
Cyfip2 K320E50.70.684, cerebellum (Kwak et al. 2008); 41–83, various brain regions (Li et al. 2009)
Flna Q2333R4.50.514, cerebellum (Kwak et al. 2008); 27–40, various brain regions (Li et al. 2009)
Flnb Q2272R20.12.8
Gabra3 I342M57.61.957, frontal lobe (Li et al. 2009)
Gria2 Q607R99.50.095–100, motor neurons (Kawahara et al. 2004); 57–98, various brain regions (Li et al. 2009)
Gria2 flip R764G51.81.358, gray matter (Maas et al. 2001); 17–65, various brain regions (Li et al. 2009)
Gria2 flop R764G54.73.0
Gria3 flip R769G83.41.348–95, various brain regions (Li et al. 2009)
Gria3 flop R769G77.04.6
Grik1 Q636R41.42.547, frontal lobe (Li et al. 2009); ∼50, cerebellum and corpus callosum (Barbon et al. 2003)
Grik2 I567V46.70.5
Grik2 Q621R45.22.2
Grik2 Y571C50.20.2
Htr2c A79.02.474–80, various brain regions (Niswender et al. 2001)
Htr2c B76.52.940–60, various brain regions (Niswender et al. 2001)
Htr2c E3.81.716–22, various brain regions (Niswender et al. 2001)
Htr2c C37.64.760–66, various brain regions (Niswender et al. 2001)
Htr2c D62.86.446–66, various brain regions (Niswender et al. 2001)
Kcna1 I400V16.52.120, cerebellum (Kwak et al. 2008); 26–59, various brain regions (Li et al. 2009)
Kcnma1 S41G2.50.7
Neil1 K242R1.00.1
  • Comparison of adenosine-to-inosine editing levels found in this study (rat cortical neurons) and the previously reported levels for the homologous editing sites in humans. All editing levels are given as percentage inosine (or a range of the percentage inosine).