Table 4  Multiple QTL mapping
PhenotypeChromosomePosition (cM)LOD scoreaPosition (Mb)1.5-LOD interval (Mb)% phenotype variancebAdditivecDominancedEffecte
Relative right testis weight2336.06105.952.2–128.55.320.35 ± 0.00.26 ± 0.12Dom. recessive
3548.06129.8108.5–143.77.19−0.16 ± 0.08−0.15 ± 0.11Musc. dominant
445.914.40108.998.8–115.313.49−0.92 ± 0.120.070 ± 0.13Musc. additive
4605.40134.5121.8–148.05.400.54 ± 0.12−0.15 ± 0.14Dom. additive
10219.3372.251.3–82.79.330.48 ± 0.08−0.08 ± 0.11Dom. additive
13310.5418.612.2–24.09.58−0.31 ± 0.080.03 ± 0.11Musc. additive
17243.7457.93.1–73.23.230.05 ± 0.08−0.44 ± 0.12Underdominant
Sperm density (binary)1713.34.0430.03.1–64.55.860.07 ± 0.03−0.16 ± 0.04Underdominant
Sperm head PC1f763.7423.413.7–44.31.900.01 ± 0.004−0.02 ± 0.01Underdominant
11394.2257.344.6–73.22.150.01 ± 0.0040.01 ± 0.01Dom. recessive
X1236.8552.522.9–58.324.35−0.05 ± 0.003Musc.
X4518.46110.098.6–128.210.51−0.03 ± 0.003Musc.
Semin. tubule areag827.84.7687.135.5–102.76.091711.39 ±372.67−185.52 ± 517.02Dom. additve
1416.14.3561.625.6–63.25.55−1621.40 ± 373.64−289.60 ± 527.09Musc. additive
16394.0288.266.8–97.25.11−1147.66 ± 360.08−1490.79 ± 537.94Musc. dominant
18334.6268.558.0–78.16.00−1497.93 ± 404.78−1724.62 ± 554.91Musc. dominant
Proximal bent tailh10124.1651.334.5–87.45.33−0.04 ± 0.10−0.02 ± 0.02Dom. additive
X24.58.8990.858.5–97.111.810.044 ± 0.007Musc.
Distal bent tailh3243.9054.728.2–72.14.71−0.023 ± 0.007−0.023 ± 0.009Dom. recessive
565.65.85139.6132.2–148.47.14−0.03 ± 0.01−0.03 ± 0.01Dom. recessive
X155.7458.546.7–98.67.000.03 ± 0.01Musc.
Headless/taillessh1503.6816.516.5–48.25.380.04 ± 0.01−0.03 ± 0.02Musc. recessive
Amorphous sperm headhX15.910.3067.752.5–70.714.360.04 ± 0.01Musc.
Total abnormal spermh1564.3532.316.5–68.75.450.06 ± 0.02−0.08 ± 0.03Musc. recessive
X1810.6368.952.5–92.713.970.09 ± 0.01Musc.
  • a All QTL are significant at a 5% genome-wide significance threshold.

  • b Percentage of phenotypic variance explained by the QTL.

  • c Additive effect: half the difference between the phenotype averages of the two homozygotes. Mean ± SD.

  • d Dominance deviation: the difference between the phenotype average of the heterozygotes and the midpoint of the phenotype averages of the two homozygotes. Mean ± SD.

  • e The subspecies allele associated with sterility and the effect of that allele (Dom., M. m. domesticusWSB; Musc., M. m. musculusPWD).

  • f Lower values of PC1 are correlated with higher levels of sterility.

  • g Residual trait scores of seminiferous tubule area regressed on testis weight. Lower values are correlated with higher levels of sterility.

  • h Arcsine square-root-transformed.