TABLE 4

Effects of daf-2 and daf-16 on developmental speed and DMPP resistance

Interacting mutation
+daf-16(0)a
daf-2 alleleL1 duration (hr)L2 duration (hr)DMPPRL2 duration (hr)DMPPR
+141011
e13681712NDND
m411723+13
m5771612NDND
m5961519+14
e13701920+11
  • For DMPP resistance (DMPPR), − refers to DMPP sensitivity as seen in the wild type and + indicates strong resistance on 0.75 mm DMPP. Developmental speed and DMPPR were determined at 20°. ND, not determined. N ≥ 25 individuals.

  • a The daf-16(0) allele used is mgDf50, except in the double mutant daf-16(m26); daf-2(m41).