Estimator | Locus | Relative pairs | Exact variance | Approximate variance | Simulation variance | Relative difference of approximation (%) |
---|---|---|---|---|---|---|

ATCT003 | 10t_{1}, 10u, 10_{2}v_{2} | 7.55 × 10^{−4} | 6.82 × 10^{−4} | 7.48 × 10^{−4} | 9.59 | |

DXS1068 | 10t_{1}, 10u_{2}, 10v_{2} | 1.54 × 10^{−3} | 1.47 × 10^{−3} | 1.50 × 10^{−3} | 4.82 | |

GATA48H04 | 10t_{1}, 10u_{2}, 10v_{2} | 1.50 × 10^{−3} | 1.48 × 10^{−3} | 1.54 × 10^{−3} | 1.52 | |

DXS1068 | 20t_{1} | 3.62 × 10^{−3} | 3.31 × 10^{−3} | 3.49 × 10^{−3} | 8.55 | |

DXS1068 | 80t_{1} | 8.08 × 10^{−4} | 7.82 × 10^{−4} | 7.93 × 10^{−4} | 3.16 | |

DXS1068 | 20u_{2} | 1.97 × 10^{−3} | 1.90 × 10^{−3} | 1.97 × 10^{−3} | 3.29 | |

DXS1068 | 80u_{2} | 4.68 × 10^{−4} | 4.60 × 10^{−4} | 4.61 × 10^{−4} | 1.71 | |

DXS1068 | 20v_{2} | 1.99 × 10^{−3} | 1.87 × 10^{−3} | 1.95 × 10^{−3} | 5.87 | |

DXS1068 | 80v_{2} | 4.64 × 10^{−4} | 4.53 × 10^{−4} | 4.56 × 10^{−4} | 2.37 | |

ATCT003 | 10t_{1}, 10u_{2}, 10v_{2} | 7.45 × 10^{−4} | 6.74 × 10^{−4} | 7.38 × 10^{−4} | 9.59 | |

DXS1068 | 10t_{1}, 10u_{2}, 10v_{2} | 1.52 × 10^{−3} | 1.45 × 10^{−3} | 1.49 × 10^{−3} | 4.82 | |

GATA48H04 | 10t_{1}, 10u_{2}, 10v_{2} | 1.49 × 10^{−3} | 1.46 × 10^{−3} | 1.53 × 10^{−3} | 1.52 | |

DXS1068 | 20t_{1} | 3.53 × 10^{−3} | 3.23 × 10^{−3} | 3.40 × 10^{−3} | 8.55 | |

DXS1068 | 80t_{1} | 8.03 × 10^{−4} | 7.77 × 10^{−4} | 7.88 × 10^{−4} | 3.16 | |

DXS1068 | 20u_{2} | 1.95 × 10^{−3} | 1.88 × 10^{−3} | 1.94 × 10^{−3} | 3.29 | |

DXS1068 | 80u_{2} | 4.67 × 10^{−4} | 4.59 × 10^{−4} | 4.60 × 10^{−4} | 1.71 | |

DXS1068 | 20v_{2} | 1.95 × 10^{−3} | 1.84 × 10^{−3} | 1.91 × 10^{−3} | 5.87 | |

DXS1068 | 80v_{2} | 4.61 × 10^{−4} | 4.51 × 10^{−4} | 4.54 × 10^{−4} | 2.37 |

The exact (Equations 15 and 16), approximate (Equation 18 inserted into Equations 15 and 16), and simulation variances were calculated for the combination of 10 male–male (

*t*_{1}), 10 male–female (*u*_{2}), and 10 female–female (*v*_{2}) full-sib pairs at the ATCT003 (*H*= 0.7794), DXS1068 (*H*= 0.7344), and GATA48H04 (*H*= 0.6476) loci as well as for sets of 20 and 80 pairs of each full-sib pair type at DXS1068. Simulation variances were calculated over 100,000 replicates. The relative difference of the approximation was computed as 100 × |approximate variance − exact variance|/(exact variance).