TABLE 1

Frequency of fixation and fitness of beneficial mutations

Frequency of fixation (%)Relative fitness
Beneficial mutationA455GA455TC1550TA455GA455TC1550T
1630+CCCGTG001.281.43
A1540C001.281.40
A1553G01.283.851.681.69
A1553T003.851.64
A1562G2019.237.691.751.651.51
A1562T1.43001.92
A1567G02.5601.94
A1592T01.2801.78
A1718G01.2801.24
A1729C1.43001.89
A455GNPNP5.26NPNP1.63
A455TNPNP47.37NPNP1.63
C1341A001.281.74
C1375T001.281.63
C1547T1.43001.45
C1550G01.2801.70
C1550T7.1411.54NP1.861.52NP
C1563A1.43001.67
C1563G01.281.281.491.56
C1591G2.8601.281.911.67
C1591T05.131.281.481.66
C1593A1.43001.82
C1607T01.281.281.391.25
C1610T001.281.40
C1619T001.281.18
C1736T2.861.281.281.761.841.39
G1561A001.281.51
G1622A001.281.65
G1624T001.281.54
G1716T001.281.58
G1724C1.43001.45
T1529C1.43001.44
T1549G2.861.2801.961.20
T1655G001.281.39
T1731C01.2801.12
T449C7.695.2601.731.31
Sum53.4255.2488.5
  • This table shows the frequency of fixation and the relative fitness of beneficial mutations identified in this study across all three genetic backgrounds used to initiate selection lines. NP indicates mutations that were not physically possible.