TABLE 2

Parameterization

SymbolDescriptionDefinition
ρLFrequency of variable Le + f + g + h
ρCFrequency of allele Cc + d + g + h
ρNFrequency of allele Nb + d + f + h
DNCDisequilibrium between N and Cd + h − ρNρC
DNLDisequilibrium between N and Lf + h − ρNρL
DLCDisequilibrium between L and Cg + h − ρNρC
DNLCThree-locus disequilibriumh − ρNρLρC
  • Reparameterizing the model in terms of the frequencies of individual factors and the disequilibrium between them facilitates biological understanding of what creates associations between factors and phenotypes.