TABLE 3

HKA Tests

GenePopulationChromosomeLnSDivχ2P-value
Winters SR data
    DoxNicewiczX552112190.056752.51<0.0001
    DoxTremontX595634120.056793.27<0.0001
    DoxWintersX60611280.056772.17<0.0001
    MDoxNicewiczX440112120.061141.22b<0.0001
    MDoxTremontX45073390.061159.31<0.0001
    MDoxWintersX45081210.061149.72<0.0001
    NmyNicewicz3R74612400.051677.34<0.0001
    NmyTremont3R74606500.051694.52<0.0001
    NmyWinters3R74611110.051659.92<0.0001
    NmyAllaTremont3R540366600.051342.85<0.0001
    NmyAllWinters3R5385121210.051120.280.0903
Begun and Whitley (2000) data
    bnbWintersX10158110.019717.990.0764
    mei-218WintersX11878140.0687
    ovoWintersX1356890.0270
    snWintersX14378280.0370
    sogWintersX1233880.0251
    XWintersX14258240.0281
    yp3WintersX1227880.0473
    AP-50Winters3R13988580.0293
    fzoWinters3R13608220.0708
    hydWinters3R17868260.0208
    OsbpWinters3R11668310.0266
    ryWinters3R13628540.0419
    T-cp1Winters3R1201890.0325
  • L, number of bases sequenced in D. simulans; n, number of D. simulans chromosomes sampled; S, number of segregating sites; Div, per-base divergence from D. melanogaster; χ2 and P-values correspond to multilocus HKA tests on 13 loci previously sequenced in D. simulans (bottom) and when data from single Winters SR genes for each North American population were added to the 13 loci (top). See text for details.

  • a Ancestral alleles were not excluded from the analysis (Nicewicz has no ancestral alleles in sample).