TABLE 2

SNPs associating with load phenotypes

Functional classGeneLocationChangeEf femaleEf maleEf allSm femaleSm maleSm allEf SNP × SexSm SNP × Sex
SignalhopscotchExonV → L0.6880.7390.981<0.001***0.3600.032*0.1720.946
Transduction0.70.3
hopscotchExon<0.001***0.025*0.981<0.001***0.076*<0.001***<0.001***0.022*
0.40.50.80.20.46.20.9
hopscotchExon<0.001***0.120<0.001***<0.001***0.7350.3720.2740.043*
0.40.20.10.7
hemipterousExonY → C0.476<0.001***<0.001***0.4450.8010.3720.3230.498
1.00.6
hemipterousExonA → S0.4760.2150.9810.8470.5200.7580.029*0.997
5.9
hemipterousExon0.2580.9730.9810.7320.1230.1680.029*0.997
6.2
Tak1Intron0.2580.9730.4040.775<0.001***<0.001***0.3040.417
0.80.5
TRAF3Exon0.999<0.001***<0.001***0.2830.3930.042*0.000***0.997
1.00.00.16.2
SecretedoutstretchedExonA → S0.4040.9730.5210.117<0.001***<0.001***0.850<0.001***
0.80.41.1
upd2Exon0.9990.3560.5360.067*0.6330.1400.9250.731
0.4
upd3Intergenic0.306<0.001***<0.001***<0.001***0.336<0.001***0.123<0.001***
0.40.20.40.20.9
Iron metabolismTsf1Exon0.999<0.001***0.012*0.9120.8140.9060.1510.997
0.90.4
HematopoesislozengeExon0.306<0.001***0.6880.092*<0.001***<0.001***<0.001***0.997
1.00.61.20.87.7
Pvf15′-UTR0.9990.9730.9810.8510.1350.4430.9870.037*
0.6
Pvf1Exon0.043*0.120<0.001***0.8320.6330.8900.9870.731
1.50.9
Pvf1Exon0.000***0.221<0.001***0.065*0.8290.2710.4870.034*
0.50.30.30.7
Pvf1Intron0.4530.2260.1340.4450.1090.028*0.8080.997
0.0
Rps6Exon0.9990.9510.9810.8200.000***0.017*0.9870.037*
0.60.21.0
Serine proteaseSer7Intergenic0.999<0.001***0.022*0.117<0.001***0.8330.029*<0.001***
0.20.10.46.20.9
  • q-values are shown for SNPs that associate with at least one load phenotype (on the basis of having FDR q < 0.1). Percentage of total phenotypic variance explained is shown for each SNP with q < 0.1 (below q-value). Change is the amino acid change associated with SNP, where applicable. Sixty-nine of 88 SNPs show no association with load phenotypes with q < 0.1. *q < 0.1, ***q < 0.001. Ef, E. faecalis; Sm, S. marcescens.