TABLE 2

Locations of suppressors

Total suppressorsExtragenic suppressorsIntragenic suppressors
Strain no. NCMamtB mutationsTotalC-terminal
4193Doublea (inactive)30141614
4238L394A (inactive)3816226
4275Frameshiftb suppressor of double (slightly active)3816223
4348, 4349, 4327, 4350Loop mutationsc (inactive)10287
Total116486830 mutations in 12 positions
  • a See Table 1.

  • b See footnote e of Table 1.

  • c Loop mutations are E121A, R122A, R185A, and K255A (see Table 1). K255A was slightly active.