TABLE 4

Comparison between simulation results and predictions for the MSD additive variance after bottlenecks

ModelkN = 1000N = 50N = 10N = 2
ISimulation40.00190.00410.00600.0045
20.00190.00410.00590.0039
10.00180.00410.00590.0036
Diffusion10.00180.00360.00580.0029
Shortcut10.00190.00350.00450.0021
IISimulation40.00240.00490.00670.0048
20.00240.00450.00580.0038
10.00240.00450.00560.0035
Diffusion10.00230.00400.00500.0025
Shortcut10.00240.00390.00430.0020
IIISimulation40.00790.01290.01280.0066
20.00790.01220.01150.0048
10.00800.01190.01090.0044
Diffusion10.00760.01030.00990.0034
Shortcut10.00800.01000.00850.0023
  • Values of the MSD additive variance obtained by simulation in the base population (N = 1000) or after 100 bottlenecks (N = 2, 10, 50, estimated from samples of 100 offspring in each line), for the different models and types of gene action (k = 1, no epistasis; k = 2, moderate synergistic epistasis; k = 4, strong synergistic epistasis), and MSD expectations (k = 1) derived from diffusion theory or a shortcut method (GarcĂ­a-Dorado 2007) are shown.