TABLE 4

Association of genotypic and phenotypic change

Colony growth phenotypea
ParentalNonparental
Genome changePTSmWr-N-RWr-T-RTotalb
No change42001052
Chromosome and BIRc21126
LOH504716
Total49151974
  • Goodness-of-fit statistic: 26.45, d.f. = 10, P < 0.005.

  • a PT, parental colony phenotype; Sm, small colony phenotype; Wr-N-R, not regulated by temperature; Wr-T-R, colony phenotype dependent on temperature.

  • b One strain exhibited two LOH events, giving a total of 74 events in 73 strains.

  • c BIR, break-induced replication.