Data | a | b | c |
---|---|---|---|

Celera data | 1.67 | 1.13 | 1.21 |

Simulated data | 1.68 (0.9) | 1.36 (0.6) | 1.39 (0.6) |

Columns indicate estimates resulting from (a) the method of Hellmann

*et al.*(2008), (b) the method presented in this article, and (c) the extension of our approach to perform calculations conditional on*observed*rather than*expected*coverage. We show the mean estimate for the data of Venter*et al.*(2001) and the mean (and RMSE) for the simulated data.