TABLE 6

TRA-F can kill sensitized males by stimulating Sxl autoregulation

% relative viability of Sxlf7,M1/Y malesb
No Dp(Sxl+)With Dp(Sxl+)
No Dp(snf+)With Dp(snf+)No Dp(snf+)With Dp(snf+)
CrossaNo hsp∷traFWith hsp∷traFNo hsp∷traFWith hsp∷traFNo hsp∷traFWith hsp∷traFNo hsp∷traFWith hsp∷traF
1Reference (n = 118)961031008864160.8
2Reference (n = 161)1099611
  • a Crosses: cm Sxlf1ct6/Y; P{snf+ w+mC}19/CyO, Cy ♂♂ × (1) ☿ w cm Sxlf7,M1 ct v/Binsinscy, y w snx2B; P{hsp83-traF+ w+mC}5.4/+; Dp(1;3)sn13a1, cm+Sxl+ct+/+ or (2) ☿ w cm Sxlf7,M1 ct v/Binsinscy, y w snx2B; Dp(1;3)sn13a1, cm+Sxl+ct+/+.

  • b Sxlf7,M1 males used as the viability reference class were 89% (cross 1) and 78% (cross 2) as viable as their Sxlf7,M1/+ sisters.