TABLE 4

Insertion sites and putative identities of resistant Drosophila lines

LineInsertion siteClosest geneFunctionAnopheles homolog
EP24252R: 2551842atsp42ejSignaling
116033L: 13424707aCG10133Phospholipase A2ENSANGG00000007839
127183R: 10902878CG12601UnknownENSANGG00000016829
12738X: 10660983CG1691mRNA bindingENSANGG00000014401
12516X: 6478974CG3168TransporterENSANGG00000010074
134253R: 3645219aCG31473Pyridoxamine-phosphate oxidase
13462X: 11636313Hsc70-3Heat-shock proteinENSANGG00000010404
13593X: 2439599trolUnknownENSANGG00000017722
13596X: 14436517aCG9413Amino acid permeaseENSANGG00000017734
13739X: 2760775CG11086UnknownENSANGG00000019046
13760X: 1129267l(3)82FdlysM domain: peptidoglycan-binding hydrolaseENSANGG00000006384
139182L: 6252967CG9486N-acetyltransferase
139952L: 7782431CG7164Unknown
164973L: 9031537aArgKArginine kinaseENSANGG00000019341
  • The insertion sites for the P. gallinaceum-resistant mutants as recorded by FlyBase or the P screen database are shown. The identity of the strongest mosquito homolog for each putative mutant is listed in the last column.

  • a The insertion site for these lines were confirmed by inverse PCR.