McDonald–Kreitman tests at MSL-binding sites vs. flanking regions

Pairwise divergenceLineage-specific divergence
Binding siteNonbinding siteBinding siteNonbinding site
D. melanogaster
D. simulans
D. yakuba
  • P, number of polymorphic sites; D, number of divergent sites from an outgroup species (D. simulans for the D. melanogaster and D. yakuba populations and D. melanogaster for the D. simulans population); D_ANC is the number of divergent sites from a reconstructed outgroup species. P-values are from Fisher's exact test. *P < 0.05.