TABLE 5

Gene dosage and gene interaction studies of lin-24 and lin-33 alleles

Genotype% Vul (n)
Wild typea0 (89)
lin-24(n432)/lin-24(n432)a92 (90)
lin-24(n4294Δ)/lin-24(n4294Δ)0 (102)
lin-24(n432)/lin-24(n4294Δ)b3 (89)
lin-24(n432)/lin-24(+)a66 (109)
lin-24(n432)/lin-24(+)/lin-24(+)c38 (56)
lin-24(n432)/lin-24(n432)/lin-24(+)d81 (117)
lin-33(n1043)/lin-33(n1043)a97 (90)
lin-33(n4514Δ)/lin-33(n4514Δ)0 (72)
lin-33(n1043)/lin-33(n4514Δ)e21 (77)
lin-33(n1043)/lin-33(+)a77 (121)
lin-33(n1043) lin-24(n432)a97 (89)
lin-33(n1043) lin-24(n4294Δ)0 (56)
lin-33(n4514Δ) lin-24(n432)0 (60)
lin-33(+) lin-24(n432)/lin-33(n4514Δ) lin-24(+)f0 (29)
lin-33(n1043) lin-24(+)/lin-33(+) lin-24(n4294Δ)g0 (12)
  • The number of Vul animals was determined as described in materials and methods. n, number of animals.

  • a These data are from Table 1.

  • b lin-24(n432) homozygous males were mated with lin-24(n4294Δ) dpy-4(e1166) hermaphrodites, and non-Dpy cross progeny were scored.

  • c This strain was of genotype unc-30(e191) dpy-4(e1166)/lin-24(n432) dpy-4(e1166); yDp1. Only non-Unc non-Dpy animals that segregated Unc Dpy and Unc Lin animals were scored.

  • d This strain was of genotype lin-24(n432) dpy-4(e1166); yDp1. Only non-Dpy animals were scored.

  • e lin-33(n1043) homozygous males were mated with lin-33(n4514Δ) unc-30(e191) hermaphrodites, and non-Unc cross progeny were scored.

  • f lin-24(n432) homozygous males were mated with lin-33(n4514Δ) unc-30(e191) hermaphrodites, and non-Unc cross progeny were scored.

  • g lin-33(n1043) homozygous males were mated with lin-24(n4294Δ) dpy-4(e1166) hermaphrodites, and non-Dpy cross progeny were scored.