TABLE 4

DSB rates in cis-plus-trans modifier models

i = hmi = hMi = Hmi = HM
hm,j)hM,j)Hm,j)HM,j)
j = hmβhβhβhEmbedded Image
    (βi,hm)
j = hmβhβhEmbedded ImageβH
    (βi,hM)
j = HMβhβhβhEmbedded Image
    (βi,Hm)
j = HMβhβhEmbedded ImageβH
    (βi,HM)
  • βi,j gives the per-haplotype DSB rate at the H locus of chromosome i when in a diploid genotype with chromosome j. For example, in a diploid genotype made up of chromosomes HM and hm, to determine the DSB rate of the HM chromosome, i = HM and j = hm, yielding Embedded Image; to determine the DSB rate of the hm chromosome, i = hm and j = HM, yielding βhm,HM = βh. In the M-dominant model, hm is set to zero; in the m-dominant model, hM is set to zero; in the no-dominance model, both hM and hm are set to zero.