Double-strand break rates in one-locus models

i = hh,j)i = HH,j)
j = hi,h)βhEmbedded Image
j = Hi,H)Embedded ImageβH
  • βi,j gives the per-haplotype DSB rate of haplotypes carrying the i allele when the other haplotype in a diploid genotype carries the j allele. In the H-dominant model, hh is set to zero; in the h-dominant model, hH is set to zero; in the no-dominance model, both hH and hh are set to zero.