APPENDIX A

Selected polymorphism statistics for simulations with μL = 10−6 without genetic drift

γ = 0γ = 0.2
mNeutral: computational10305070901030507090
Ne = 103Ne = 103
nA1.0090.005912.4501.04018.9501.15124.1501.29029.7001.67741.8001.85710.3501.03816.3501.11319.7501.06320.8501.26619.7001.822
H0.00230.00170.8740.0100.9180.0040.9330.0050.9440.0040.9590.0030.8530.0120.8990.0070.9130.0070.9180.0070.8950.010
mean(sij)0.1830.0070.1480.0050.1170.0040.0720.0020.0110.0000.1580.0070.1220.0040.0920.0040.0550.0020.0140.001
mean(hij)0.6860.0210.5300.0200.3750.0110.2100.0070.0520.0040.4440.0180.3340.0160.2340.0100.1290.0060.0280.003
γ = 0.4γ = 0.8
mNeutral: analytic10305070901030507090
Ne = 103Ne = 103
nA1.0168.6000.89312.4501.04014.6001.06815.2001.34610.6501.2504.2500.5105.4500.6896.1000.6654.5000.6892.9500.643
H0.0020.8240.0150.8690.0110.8810.0110.8750.0110.7990.0280.6440.0370.6760.0560.6720.0510.6110.0750.4100.099
mean(sij)0.1290.0070.0960.0040.0710.0030.0410.0020.0130.0010.0580.0040.0420.0030.0310.0020.0170.0010.0040.001
mean(hij)0.2710.0140.2010.0120.1390.0080.0740.0050.0150.0030.0550.0090.0350.0080.0220.0060.0130.0040.0030.001
γ = 0γ = 0.2
mNeutral: computational10305070901030507090
Ne = 104Ne = 104
nA1.20.02718.3501.20926.6001.59236.2501.40044.9502.41983.1503.64015.2001.19521.7501.45626.8001.54928.1002.16530.2501.497
H0.01880.00450.9090.0070.9350.0040.9520.0030.9570.0040.9720.0010.8910.0090.9200.0050.9350.0040.9320.0070.9240.006
mean(sij)0.1690.0080.1460.0080.1100.0030.0640.0020.0080.0000.1450.0070.1170.0050.0830.0040.0470.0020.0100.000
mean(hij)0.6900.0230.5180.0120.3630.0090.1940.0080.0440.0020.4460.0190.3280.0100.2310.0080.1200.0070.0240.002
γ = 0.4γ = 0.8
mNeutral: analytic10305070901030507090
Ne = 104Ne = 104
nA1.20912.5501.15116.6501.35819.3501.24218.5501.86714.7501.1455.8500.7956.3000.6687.5000.9276.6001.2434.0500.674
H0.01960.8670.0150.8940.0070.9110.0070.8950.0140.8470.0160.6970.0510.7180.0300.7400.0440.6630.0870.5100.084
mean(sij)0.1190.0070.0900.0040.0610.0030.0350.0020.0090.0010.0550.0040.0400.0030.0260.0020.0150.0010.0040.000
mean(hij)0.2700.0160.1960.0080.1390.0060.0700.0060.0130.0010.0510.0090.0350.0060.0250.0050.0120.0030.0020.001
γ = 0γ = 0.2
mNeutral: computational10305070901030507090
Ne = 105Ne = 105
nA3.30.198424.9001.62131.8501.49345.7502.33261.8503.501143.5506.60820.5001.65526.5501.67333.4002.00338.6003.17136.2503.239
H0.17540.0280.9300.0070.9440.0030.9570.0030.9650.0020.9770.0010.9160.0090.9290.0050.9420.0040.9430.0060.9280.008
mean(sij)0.1610.0070.1440.0050.1050.0040.0570.0010.0060.0000.1370.0070.1150.0050.0770.0030.0400.0010.0080.000
mean(hij)0.6890.0210.5050.0100.3390.0070.1730.0080.0350.0020.4450.0180.3210.0080.2140.0060.1050.0070.0190.002
γ = 0.4γ = 0.8
mNeutral: analytic10305070901030507090
Ne = 105Ne = 105
nA3.49916.7001.40820.6501.23424.5001.61823.8502.58017.5502.1217.4001.0497.5500.8598.2001.0516.3501.3734.5000.847
H0.16670.8940.0130.9050.0070.9200.0050.9060.0130.8560.0190.7440.0430.7500.0280.7580.0300.6280.0760.5060.080
mean(sij)0.1120.0060.0880.0040.0560.0020.0310.0020.0070.0000.0510.0040.0370.0020.0240.0020.0140.0010.0030.001
mean(hij)0.2710.0150.1920.0070.1270.0050.0600.0060.0100.0010.0530.0090.0350.0050.0220.0030.0090.0030.0010.001
  • Mean (left value) ±95% confidence interval (right value). nA, number of alleles; H, heterozygosity; mean(sij), mean selection strength experienced by genotypes; mean(hij), mean proportionate heterozygote advantage relative to fittest homozygote. Expected number of alleles and heterozygosity under neutrality are presented for each population size on the left (95% confidence intervals for computational estimates only). Neutral expectations were calculated both computationally (see text) and analytically (heterozygosity from Kimura and Crow 1964; expected number of alleles from Ewens 2004).