TABLE 2

Aβ peptide levels

MutationAβ eye phenotypeSoluble AβP-value (soluble)Total AβP-value (total)Effect
Aβ/+100576.5 ± 22.9
EP(X)0308S140757.3 ± 18.30.001Total 30% up
ATP7EY07895E130 ± 15.50.22NTaNo change
Dsp1EP(X)0355E231683.3 ± 9.30.005Total 30% up
Dsp1KG06700E157 ± 1060.59NTNo change
svrEP(X)0356E157 ± 39.60.29395.3 ± 39.30.004Total 30% down
svrKG02090E216 ± 70.03NTSoluble 100% up
gEP(X)0514S174 ± 1.40.01682.3 ± 42.30.011Soluble 75% up
CG2924EP(X)1596S171662.8 ± 55.70.034No change
EP(2)0684esgENT692.0 ± 12.30.003Total 20% up
EP(2)0386E200521.2 ± 84.80.221No change
Elb9E134NT
CG7231EP(2)2510E110 ± 28.30.70NTNo change
EP(3)0595bE119.7 ± 13.50.13563.5 ± 96.40.796No change
EP(3)1051E100 ± 28.31.00708.2 ± 4.10.002Total 23% up
SnfγEP(3)3015bE90726.6 ± 10.40.001Total 26% up
SNFγKG10152E187.5 ± 9.20.05NTSoluble 87% up
EP(3)3041E83 ± 4.20.11NTNo change
EP(3)3099E185.5 ± 40.30.20530.2 ± 60.10.192No change
mubEP(3)3108E200 ± 62.20.26733.7 ± 23.20.001Total 27% up
mub04093NE123 ± 12.70.24NTNo change
EP(3)3348S25.5 ± 6.30.04503.9 ± 19.70.027Soluble 75% down
SAP130EY10279E257 ± 39.6NTSoluble 150% up
CG2924EY02142NE123.3 ± 430.45NTNo change
EP(3)3405S83.5 ± 360.63NTNo change
EP(3)3470E63.5 ± 17.60.21600.3 ± 19.30.244No change
nep2EP(3)3549S27.5 ± 3.50.02190.1 ± 135.70.001Total/soluble 70% down
EP(3)3603S148 ± 9.10.01516.4 ± 83.60.184Soluble 50% up
CG6767KG00420E138 ± 29.80.16NTNo change
  • See Table 1 footnotes for definitions of abbreviations.

  • a Not tested.