TABLE 3

Mitotic recombination rates between the HR (cβ2-100%) and HER (cβ2-4ns) substrates

Recombination rate × 108
GenotypeHR(C.I.)HER(C.I.)HER:HR ratea
Wild type135(119–158)8.2(7.1–8.7)0.061(0.045–0.073)1.0
msh3Δ msh6Δ251(206–283)266(227–290)1.1(0.8–1.4)17
pol30-521020(758–1490)131(115–305)0.13(0.077–0.40)2.1
pol30-104432(306–680)25(15–30)0.058(0.02–0.098)0.95
pol30-201225(174–364)42.3(36.3–52.2)0.19(0.10–0.30)3.1
pol30-204535(389–578)42.2(35.8–53.2)0.079(0.062–0.14)1.3
pol30-201 msh3Δ msh6Δ613(437–1000)382(348–473)0.62(0.35–1.1)10
pol30-201, 204705(483–886)91.8(70.7–119)0.13(0.08–0.25)2.1
  • C.I. = 95% confidence interval.

  • a 99% confidence limits of the HER:HR ratios are shown in parentheses and were calculated as described in materials and methods. The underlined numbers are the HER:HR rates normalized to wild type.