Sequenced mutations | 237 | 227 |

Mutations at locus | 207 | 227 |

Fraction at locus | 0.87 | 1.00 |

Mutation rate to resistance | 5.43 | 15.2 |

Rate of loss of function of locus | 4.74 | 15.20 |

Nonsense mutations found | 64 | 70 |

Fraction of total mutations | 0.31 | 0.31 |

No. of unique nonsense mutations | 42 | 54 |

Fraction of possible unique nonsense mutations observed | 0.34 | 0.24 |

Missense mutations found | 103 | 80 |

Fraction of total mutations | 0.50 | 0.35 |

No. of unique missense mutations | 66 | 63 |

Insertion/deletion/other mutations found | 40 | 77 |

Fraction of total mutations | 0.19 | 0.34 |

Base pairs | 804 | 1773 |

Possible substitutions (bp × 3) | 2412 | 5319 |

Possible nonsense substitutions | 123 | 226 |

Possible nonsense substitutions leading to resistance^{a} | 123 | 226 |

Fraction of nonsense substitutions leading to resistance^{a} | 1 | 1 |

Possible missense substitutions | 2289 | 5093 |

Possible missense substitutions at *URA3* leading to resistance | 193 | |

Possible missense substitutions at *CAN1* leading to resistance | | 264 |

Fraction of missense substitutions leading to resistance | 0.08 | 0.05 |

Target size for loss of function via base pair substitution (bp) | 104 | 163 |

Target size for loss of function via insertion/deletion/other^{b} (bp) | 804 | 1773 |

Effective target size (bp) | 125 | 236 |

Phenotypic mutation rate (10^{−8}) | 5.43 | 1.52 |

Mutation rate at locus (10^{−8}) | 4.75 | 1.52 |

Mutation rate per base pair at locus (10^{−10}) | 3.80 | 6.44 |