Comparison of efficiency of FSHAP, FAMHAP, FAMHAP_nit, and FBAT in the case of families with different numbers of children (five SNPs) from 100 data sets

60 families with 4–8 children each (on average 5.90 children/family)
Discrepancy0.0043 (0.0006)a0.0209 (0.0009)b0.0190 (0.0009)b0.0223 (0.0011)b
Identification rate0.9794 (0.0042)a0.9136 (0.0084)b0.8401 (0.0132)c0.9707 (0.0046)a
Error rate in parents0.1125 (0.0030)a0.1311 (0.0094)b0.2470 (0.0250)b0.1326 (0.0043)c
Error rate in offspring0.0080 (0.0011)a0.0192 (0.0016)b0.1355 (0.0190)c0.0204 (0.0015)b
Running time (s)0.42090.80010.93019.9700
60 families with 2–10 children each (on average 5.93 children/family)
Discrepancy0.0035 (0.0005)a0.0250 (0.0012)b,c0.0233 (0.0012)b0.0282 (0.0012)c
Identification rate0.9829 (0.0039)a0.9271 (0.0080)b0.8539 (0.0138)c0.9658 (0.0051)d
Error rate in parents0.1528 (0.0030)a0.1716 (0.0043)b0.2608 (0.0245)c0.2084 (0.0070)d
Error rate in offspring0.0054 (0.0008)a0.0186 (0.0020)b0.1333 (0.0210)c0.0354 (0.0016)d
Running time (s)0.21426.48006.49002.9600
  • FAMHAP_nit: FAMHAP without the progressive-extension technique being implemented. Standard error is in parentheses.

  • a,b,c,d Means with different superscripts within one row differ significantly at the α < 0.01 significance level.