TABLE 3

Functional categorization of genes that give a mutant eye phenotype

Gene function categoryX (%)Auto (%)All (%)
Apoptosis0 (0)3 (1)3 (1)
Cell adhesion/ECM4 (4)7 (2)11 (2)
Cell cycle1 (1)10 (2)11 (2)
Channel and transporter5 (5)12 (3)17 (3)
Chaperone and protein folding/binding1 (1)13 (3)14 (3)
Chromatin remodeling/binding1 (1)10 (2)11 (2)
Cytoskeleton6 (6)23 (6)29 (6)
DNA replication, repair, and recombination2 (2)4 (1)6 (1)
Intracellular transport6 (6)23 (6)29 (6)
Metabolic enzyme2 (2)22 (5)24 (5)
Mitochondrial5 (5)16 (4)21 (4)
Novel19 (17)74 (18)93 (18)
Other cellular processes3 (3)6 (1)9 (2)
Protein modification/metabolism7 (6)22 (5)29 (6)
RNA binding/processing5 (5)39 (9)44 (8)
Signal transduction22 (20)48 (12)70 (13)
Transcription and gene regulation12 (11)46 (11)58 (11)
Translation and protein synthesis8 (7)25 (6)33 (6)
Ubiquitination/degradation0 (0)8 (2)8 (2)
  • Numbers of genes on the X chromosome, autosomes (auto), or all chromosomes were identified on the basis of publicly available information from FlyBase, using Drosophila melanogaster genome annotation 5.1. Gene ontology for each gene that gives a phenotype was used to assign a single functional category. Parentheses indicate percentage of the genes on the X chromosome or autosomes belonging to that category.