TABLE 3

Gonadal dysgenesis in the offspring of TP; Birm stocks

Stocks with attached-X ♀♀Stocks with homozygous X ♀♀
StockReplicateaNo. of vialsNo. of ♀♀% GD ± SEbNo. of vialsNo. of ♀♀% GD ± SEb
Stocks with Birm autosomesc
w1a25385100.0 ± 0.02343899.1 ± 0.4
1b23267100.0 ± 0.03051998.5 ± 0.6
2a941100.0 ± 0.03055697.2 ± 0.9
2b25293100.0 ± 0.019360100.0 ± 0.0
TP51a25367100.0 ± 0.03058417.1 ± 4.5
1b25355100.0 ± 0.02647318.1 ± 3.8
2a25284100.0 ± 0.0274820.7 ± 0.3
2b25453100.0 ± 0.0263841.9 ± 0.8
TP61a25424100.0 ± 0.0111980.9 ± 0.9
2a2528199.6 ± 0.4364161.2 ± 0.8
2b2326199.6 ± 0.4375072.3 ± 0.9
Control attached-X stocksd
w124373100.0 ± 0.0
224328100.0 ± 0.0
TP5124460100.0 ± 0.0
22529599.7 ± 0.2
TP6124411100.0 ± 0.0
22539899.5 ± 0.4
π21223282.1 ± 1.1
Control free-X stocks
w30600100.0 ± 0.0
TP53259685.4 ± 3.4
TP62426231.6 ± 6.0
M5B#12427794.8 ± 2.3
  • a Among the attached-X stocks, replicates 1, 1a, and 1b carried C(1)DX, y f and replicates 2, 2a, and 2b carried C(1)DX, y w f.

  • b Unweighted mean percentage of GD ± standard error (SE). Note that in the tests of females with attached-X chromosomes, GD is induced by autosomes and a Y chromosome derived from the Harwich P strain whereas, in the tests of females with homozygous X chromosomes, it is induced by autosomes and an X chromosome from this strain.

  • c Stocks with attached-X chromosomes and Birm autosomes were created by repeatedly backcrossing males that carried a particular free X chromosome to attached-X females that carried the Birm autosomes. Homozygous X stocks were created by crossing males from each of the attached-X stocks to M5B#1 females and then using the balancing properties of the M5 chromosome to make the free X chromosome homozygous.

  • d The π2 attached-X stock was derived from a P strain. It contains numerous P elements and carries the double P-element insertion mutation snw on its free X chromosome (Engels 1979b). The only P elements present in the other control attached-X stocks were TP5 or TP6.