TABLE 1

Reporter gene assays of 10 human and chimpanzee promoters

GeneHuman averageaHuman SDChimpanzee averageaChimpanzee SD
BTAF1265.842.1331.150.7
CTSC*151.910.1177.418.7
GOSR1*122.58164.412.5
DUSP6*83.22.375.46.4
DDA3*38.52.8745.95.4
BAT83.50.183.50.2
LGALS43.30.53.10.6
ACADSB2.10.251.30.38
FCN31.90.31.40.38
TIMP30.90.10.90.1
  • * The difference in activity between the human and the chimpanzee promoters is significant at P < 0.05 (see Figure 2).

  • a Average luminescence for each construct over 5 replicates (15 in the case of DDA3) was standardized by the average luminescence of the control (empty Luciferase vector).