TABLE 2

Sum of squares of differences between simulated and experimental frequencies of (1) MLH1 foci in 10 different bins along bivalents having one, two, and three or more foci (patterns of MLH1 density) and (2) bivalents with zero, one, two, and three or more MLH1 foci (frequency of bivalent classes) for the chi-square and FIC models

Patterns of MLH1 density (1)Frequency of bivalent classes (2)
Chromosomeχ2FICRatioaχ2FICRatioa
12.45 × 10−31.16 × 10−32.118.48 × 10−42.86 × 10−42.97
25.00 × 10−33.30 × 10−31.526.07 × 10−32.92 × 10−32.08
38.88 × 10−36.61 × 10−31.341.98 × 10−51.63 × 10−40.12
43.30 × 10−32.81 × 10−31.171.29 × 10−42.07 × 10−40.62
52.31 × 10−33.24 × 10−30.716.22 × 10−42.74 × 10−42.27
64.20 × 10−32.29 × 10−31.835.68 × 10−31.25 × 10−5454.68
72.74 × 10−32.54 × 10−31.082.30 × 10−34.74 × 10−548.62
81.53 × 10−31.01 × 10−31.511.48 × 10−31.32 × 10−31.12
92.41 × 10−31.50 × 10−31.611.87 × 10−33.37 × 10−45.55
104.51 × 10−33.33 × 10−31.366.43 × 10−31.59 × 10−34.04
111.74 × 10−31.29 × 10−31.357.10 × 10−42.45 × 10−42.90
121.73 × 10−23.88 × 10−34.464.28 × 10−27.79 × 10−454.91
131.50 × 10−21.68 × 10−38.935.24 × 10−23.30 × 10−315.89
141.46 × 10−37.46 × 10−41.959.46 × 10−43.68 × 10−42.57
151.13 × 10−23.19 × 10−435.362.87 × 10−21.16 × 10−324.82
161.51 × 10−21.66 × 10−39.095.70 × 10−24.46 × 10−312.77
179.45 × 10−36.25 × 10−415.123.68 × 10−21.08 × 10−334.13
181.08 × 10−21.29 × 10−38.365.08 × 10−23.06 × 10−316.59
194.19 × 10−33.45 × 10−412.148.99 × 10−35.05 × 10−417.81
Pooled2.27 × 10−34.42 × 10−45.157.93 × 10−35.17 × 10−415.34
  • a Ratios between sums of squares of differences obtained for chi-square and FIC models: ratio values <1 indicate a better fit to the data for the chi-square model, whereas values >1 indicate a better fit for the FIC model. Data are given for individual chromosomes (1–19) and by pooling MLH1 foci or bivalent counts over all chromosomes (pooled).