TABLE 1

Nucleoporin activation is repressed by glucose

lexA fusionaR (glucose)D (no glucose)D/R ratiob
NUP842303c5185c2.3
NUP145C79934034.3
NUP1201917664.0
NUP145N655218.0
SEC1317875.1
NUP1337578.1
STE121241331.1
lexA alone<0.1<0.1
  • a C-terminal fusion to the lexA DNA-binding domain. The classically described STE12 activator and lexA DNA-binding domain alone are shown as controls.

  • b Ratio of derepressed to repressed reporter gene expression.

  • c lexA-driven β-galactosidase activity. Four independent determinations of β-galactosidase activity (units per milligram of total protein) were averaged; standard error of the mean for each value was <10%.