TABLE 3

Accumulated probability of LOD score, P(LOD < x), from a permutation test

Population size 200Population size 300
ADDADD + EPIADDADD + EPI
xH = 0.8H = 0.5H = 0.8H = 0.5H = 0.8H = 0.5H = 0.8H = 0.5
2.00.90180.94340.92550.96100.82500.87730.87710.9214
2.50.93700.96890.95380.97960.86070.91010.90680.9526
3.00.96090.98230.97240.98930.88910.93510.92610.9720
3.50.97570.99000.98360.99430.91310.95430.94010.9837
4.00.98570.99360.99020.99730.93280.96910.95190.9913
4.50.99210.99660.99500.99870.94770.98000.96070.9953
5.00.99550.99790.99750.99930.95970.98750.96850.9977
5.50.99730.99910.99880.99970.96960.99210.97430.9986
6.00.99870.99960.99940.99990.97720.99500.97910.9993
  • ADD, additive genetic model as defined in Table 2; ADD + EPI, additive and epistasis genetic model as defined in Table 2; H, heritability in the broad sense.