TABLE 1

Markers associated with the restoration of sperm-head morphology

PositionB/BM/B
ChromosomeMicrosatellite markerGenetic (cM)Physical (Mbp)RestoredNonrestoredRestoredNonrestoredP-valuea
1D1Mit37317.026.7261150.082
D1Mit21325.743.7291120.003
D1Mit21432.158.6291120.003
D1Mit4643.176.0210111<0.001
D1Mit4954.587.1281130.011
D1Mit33862.0Not mapped181130.003
D1Mit28871.5149.3261150.082
3D3Mit20077.3148.6103380.038
7D7Mit210.50.092490.019
D7Mit26711.018.592490.019
D7Mit22818.027.482590.047
D7Mit20034.567.293480.100
8D8Mit1491.05.992460.081
9D9Mit34655.0100.3251140.074
11D11Mit8937.066.7371040.095
D11Mit7054.093.8510810.013
D11Mit5262.0102.0510810.013
D11Mit30271.0113.849920.019
D11Mit6971.0120.749920.019
16D16Mit15734.151.259820.047
17D17Mit12356.791.9115260.082
  • Of 144 markers throughout the genome, only significant markers are listed in the table (threshold value, P = 0.10). B/B, homozygous for B6 alleles; M/B, heterozygous for MSM and B6 alleles. Positions of the markers on the genetic map were retrieved from Mouse Genome Informatics (Jackson Laboratory). Marker positions on the physical map were retrieved from the Mouse Ensemble Database.

  • a Fisher's exact test was used to determine the P-value for the association of the restoration of sperm-head morphology and genotype at each marker.