TABLE 3

Association tests for COMT haplotypes with schizophrenia

Two-SNP haplotypesaThree-SNP haplotypea: H4
P-values forH1H2H3
Entropy1.9e-0092.7e-0062.9e-0061.5e-012
Exponential1.2e-0139.5e-0091.8e-0058.0e-014
Quadratic7.5e-0131.5e-0089.5e-0064.0e-014
Reciprocal1.4e-0108.3e-0082.4e-0062.9e-013
χ2 b1.4e-0045.7e-0031.1e-0034.5e-004
  • All data (including males and females) are used in the analysis.

  • a H1, rs737865–rs165599; H2, rs737865–rs165688; H3, rs165599–rs165688; H4, rs165688–rs737865–rs165599.

  • b P-values reported by Shifman et al. (2002).