TABLE 1

Genetic variants at 6p22 and their statistics

Sample sizeNo. of variantsaπ (%)bParameter θNeutrality testsc
PopulationSingletonDoubletonOthersTotalθwθΠTajima's DFu and Li's DFu and Li's F
All samples12840 (12.3)7 (6.1)19 (47.6)660.07012.277.29−1.25 (−1.37)−5.59** (−1.81)−4.23** (−1.66)
Africans4031 (12.0)7 (6.0)13 (33.0)510.06911.997.22−1.35 (−1.38)−3.33** (−1.88)−2.88** (−1.81)
Non-Africans8211 (6.0)1 (3.0)18 (21.0)300.0646.036.660.32 (−1.38)−1.65 (−1.87)−0.99 (−1.74)
Asians427 (5.6)1 (2.8)16 (15.6)240.0615.586.310.42 (−1.42)−0.47 (−1.88)−0.16 (−1.77)
Europeans408 (5.9)1 (2.9)16 (16.2)250.0675.886.950.59 (−1.39)−0.67 (−1.99)−0.23 (−1.87)
  • ** Significant at the 1% level.

  • a The numbers of variants expected from K = θan are given in parentheses.

  • b Nucleotide diversity after excluding indels.

  • c The critical values were obtained from 5000 simulated samples and are given in parentheses.